Volume 3, Issue 3 And 4 (10-2015)                   J Surg Trauma 2015, 3(3 And 4): 57-59 | Back to browse issues page

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Student Research Committee, Faculty of Medicine, Birjand University of Medical sciences Birjand, Iran
Abstract:   (4209 Views)

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias.Acute abdominal pain is one of the PNH clinical manifestations due to venous thrombosis of intra-abdominal sites including hepatic, portal, mesenteric, and splenic veins.Eculizumaband allogeneic bone marrow transplantation (BMT) arethe only widely effective therapies for these patients.

We report a case of PNH disorder which presented with abdominal pain and mild tenderness. Abdominal X ray and sonography revealed intra-peritonealfree fluid and air. At laparotomy, an ischemic segment of jejunum with stricture and perforationwith mesenteric venous thrombosis were found. The patient also had a history of hepatic vein thrombosis two years before.

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Type of Study: Case Report | Subject: General Surgery
Received: 2016/10/3 | Accepted: 2016/11/26 | Published: 2016/12/25 | ePublished: 2016/12/25

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