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:: دوره 4، شماره 3 و 4 - ( 5-1395 ) ::
جلد 4 شماره 3 و 4 صفحات 44-46 برگشت به فهرست نسخه ها
Effect of Avastin on intraocular pressure before and after intravitreal injections
چکیده:   (125 مشاهده)
Introduction: Intravitreal Avastin (bevacizumab) injection is reportedly accompanied by ocular and systemic side-effects. Our enquiry assesses whether there are any differences between intraocular pressure (IOP) in baseline and on the day after injection in patients treated for retinal disease.
Methods: In this experimental study, 82 eyes with retinal diseases that had indication for anti-VEGF and were treated with injections of intravitreal bevacizumab were taken as the case group, and 82 healthy eyes were considered as controls. The IOP was measured by non-contact tonometry in both the healthy eyes and the eyes with retinal diseases before and 24 hours after intervention. Data were analyzed by paired t test and independent t-test in SPSS 19.0 software. Significance level was set at P <0.05.
Results: Results of the study showed that the mean IOP before injection was not significantly different in either groups (p=0.51). However, it was significantly lower after injection than before it in both case and control eyes (p<0.01). The mean IOP changes before and after infusion in the case and control eyes did not differ significantly (p=0.30).
Conclusions: Our study did not find an increased IOP in bevacizumab-treated eyes when compared to fellow control eyes. Further studies with a greater sample size are needed to evaluate whether an increased number of ranibizumab injections is associated with IOP changes.
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نوع مطالعه: پژوهشي |
دریافت: ۱۳۹۵/۹/۲ | پذیرش: ۱۳۹۶/۵/۱۳ | انتشار: ۱۳۹۶/۵/۱۳
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Heydari B, Heydari S R, Yaghoobi G. Effect of Avastin on intraocular pressure before and after intravitreal injections. Journal of Surgery and Trauma . 2016; 4 (3 and 4) :44-46
URL: http://jsurgery.bums.ac.ir/article-1-77-fa.html
Effect of Avastin on intraocular pressure before and after intravitreal injections. نشریه جراحی و تروما. 1395; 4 (3 و 4) :44-46

URL: http://jsurgery.bums.ac.ir/article-1-77-fa.html

دوره 4، شماره 3 و 4 - ( 5-1395 ) برگشت به فهرست نسخه ها
نشریه جراحی و تروما Journal of Surgery and Trauma
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