AU - Mottaghi Moghaddam Shahri, Hassan AU - Yaghubi, Mohsen AU - Ghasemi, Reza AU - Chambari, Milad AU - Hosseinzadeh Maleki, Mahmood TI - Clinical outcomes of pulmonary valve replacement surgery in pediatrics: a single-center experience long-term study PT - JOURNAL ARTICLE TA - surgery JN - surgery VO - 10 VI - 2 IP - 2 4099 - http://jsurgery.bums.ac.ir/article-1-307-en.html 4100 - http://jsurgery.bums.ac.ir/article-1-307-en.pdf SO - surgery 2 ABĀ  - Introduction: Heart valve disease in pediatricsis an increasing global concern, especially in developing countries. This study aims to determine the clinical outcomes of pulmonary valve replacement (PVR) surgery in pediatrics. Methods: The authors retrospectively identified all pediatrics undergoing PVR surgery at Imam Reza hospital (Mashhad, Iran) between 2000 and 2020. Their medical records were reviewed for demographic characteristics, clinical data (intra-operative and postoperative), and follow-up results. Echocardiography and electrocardiography were performedonall patients before the surgery and periodically after the surgery. Results: Among 50 pediatrics undergoing surgical PVR, 38 (76%) were female and others were male (14%), with a mean age of 10.39±5.31 years. The leading cause of PVR was the Tetralogy of Fallot. There was a significant relationship between age at the time of surgery and the size of the pulmonary valve(P=0.02).There were also statistically significant differences between QTc intervals before and after surgery (P=0.001). Further more, there was a significant correlation between QTc intervals before and after surgery and the ageof pediatrics at the time of surgery (P=0.01, r=-0.6).There was also a statistically significant relationship between the ICU stay (P=0.01) and the weaning time of the mechanical ventilation (P=0.03). Conclusion: It is recommended that this procedure ispostponed as much as possible to decrease postoperative life-threatening events in pediatrics.In addition, if this surgery is conducted with good surgical and nursing management, it can be safe with low complications among other cardiac valve procedures. CP - IRAN IN - Mashhad University of Medical Sciences, Mashhad, Iran LG - eng PB - surgery PG - 71 PT - Research YR - 2022