en جراحی قلب Heart Surgery پژوهشي Research <ul> <li style="text-align: justify;"><strong>Introduction:</strong> Heart valve disease in pediatricsis an increasing global concern, especially in developing countries. This study aims to determine the clinical outcomes of pulmonary valve replacement (PVR) surgery in pediatrics.</li> <li style="text-align: justify;"><strong>Methods:</strong> The authors retrospectively identified all pediatrics undergoing PVR surgery at Imam Reza hospital (Mashhad, Iran) between 2000 and 2020. Their medical records were reviewed for demographic characteristics, clinical data (intra-operative and postoperative), and follow-up results. Echocardiography and electrocardiography were performedonall patients before the surgery and periodically after the surgery.</li> <li style="text-align: justify;"><strong>Results:</strong> Among 50 pediatrics undergoing surgical PVR, 38 (76%) were female and others were male (14%), with a mean age of 10.39&plusmn;5.31 years. The leading cause of PVR was the Tetralogy of Fallot. There was a significant relationship between age at the time of surgery and the size of the pulmonary valve(P=0.02).There were also statistically significant differences between QTc intervals before and after surgery (P=0.001). Further more, there was a significant correlation between QTc intervals before and after surgery and the ageof pediatrics at the time of surgery (P=0.01, r=-0.6).There was also a statistically significant relationship between the ICU stay (P=0.01) and the weaning time of the mechanical ventilation (P=0.03).</li> <li style="text-align: justify;"><strong>Conclusion:</strong> It is recommended that this procedure ispostponed as much as possible to decrease postoperative life-threatening events in pediatrics.In addition, if this surgery is conducted with good surgical and nursing management, it can be safe with low complications among other cardiac valve procedures.</li> </ul> Congenital Heart Disease, Pulmonary Valve Atresia, Pulmonary Valve Insufficiency, Pulmonary Valve Stenosis, Tetralogy of Fallot 71 76 http://jsurgery.bums.ac.ir/browse.php?a_code=A-10-57-4&slc_lang=en&sid=1 Hassan Mottaghi Moghaddam Shahri mottaghih@mums.ac.ir 10031947532846007902 10031947532846007902 No Associate Professor, Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mohsen Yaghubi n.m.yaghubi@gmail.com 10031947532846007903 10031947532846007903 No MSc in Extra-Corporeal Technology, Department of Extra-Corporeal Circulation, Razavi Hospital, Imam Reza International University, Mashhad, Iran Reza Ghasemi n.m.yaghubi@gmail.com 10031947532846007904 10031947532846007904 No Assistant Professor, Department of Cardiology, 9-Day Hospital, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran Milad Chambari mottaghih@mums.ac.ir 10031947532846007905 10031947532846007905 No Department of Pediatrics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mahmood Hosseinzadeh Maleki hoseinzadehmalekim@mums.ac.ir 10031947532846007906 10031947532846007906 Yes Associate Professor, Department of Cardiac Surgery, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran