Journal of Surgery and Trauma

en Comparison of Effects of 0.5% Silver Nitrate and 10% Sucralfate on the Healing of Second-degree Burn Wounds in Burn Patients: A Randomized Controlled Clinical Trial Study پوست Dermatology پژوهشي Research <div style="text-align: justify;">Introduction: While a substantial number of studies have examined the use of silver nitrate in burn treatment, a comparative analysis of sucralfate and silver nitrate in this context has not yet been conducted. This study aimed to compare the effects of silver nitrate and sucralfate on the healing of second-degree burn wounds in burn patients at Imam Reza Hospital in Birjand. Methods: This randomized controlled clinical trial was performed on 60 patients with second-degree burns. Participants were randomly assigned to two groups: group A, which consisted of patients treated with a 0.5% silver nitrate dressing, and group B, which included those treated with a 10% sucralfate dressing. Initially, the Kolmogorov-Smirnov test was used to assess the normal distribution of the data. If the data were found to be normal, one-way analysis of variance and independent t-tests were employed. In the absence of normality, the Friedman and Mann-Whitney tests were used. Results: Based on the findings, in the intervention group (B), 5 cases of bacterial colonization were positive, while 25 were negative. However, in the control group (A), 11 individuals had positive bacterial colonization. In both the intervention and control groups, the mean Bates-Jensen wound score on day 3 was significantly higher than on days 7 and 21 (p<0.001). Additionally, the mean Bates-Jensen wound score on day 7 was significantly higher compared to day 21 (p<0.001). In terms of pain score, the median score on day 3 was significantly higher than on days 7 and 21 (p<0.001). Conclusion: Based on this study, the administration of 10% sucralfate, compared to the conventional approach, significantly enhanced wound healing.</div> Burns, Silver Nitrate, Sucralfate, Wounds and Injuries 137 143 http://jsurgery.bums.ac.ir/browse.php?a_code=A-10-168-11&slc_lang=en&sid=1 Mohsen Najmaddini Dr.mohsen_najmaddini@yahoo.com 100319475328460011795 0000000307418234 No Department of Surgery, Cancer Surgery Group, Omid Hospital Associate Professor of Surgical Oncology ,Mashhad University of Medical Sciences, Mashhad, Iran Mohammad sadegh Afzali sardu sadeghafzali631@yahoo.com 100319475328460011796 100319475328460011796 No Department of Surgery, Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran Seydamalek Dadkhah Seyda.dadkhah@gmail.com 100319475328460011797 100319475328460011797 No Department of Nursing, School of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran Mahboobe Doostkami Mahbobedostkam@gmail.com 100319475328460011798 100319475328460011798 No Department of Operating Room, School of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran Ehsan Soltani soltanie@mums.ac.ir 100319475328460011799 100319475328460011799 No Department of Surgery, Cancer Surgery Group, Omid Hospital, Associate Professor of Surgical oncology, Mashhad University of Medical Sciences,Mashhad, Iran Fatemeh Shakhsemempour f.emampour@gmail.com 100319475328460011800 100319475328460011800 No Department of Anesthesiology, School of Medicine ,Birjand University of Medical Sciences, Birjand, Iran Fidan Shabani fidannahal@yahoo.com 100319475328460011801 100319475328460011801 No Cardiovascular Nursing Research center, Rajaie Cardiovascular Institute, Tehran, Iran Mozhgan Bahramian bahramianmozhgan@gmail.com 100319475328460011802 0009-0002-6334-3839 No School of Medicine, Birjand university of Medical Science, Birjand, Iran Maryam Bahramian m.bahramian97@gmail.com 100319475328460011803 100319475328460011803 No School of Medicine, Birjand university of Medical Science, Birjand, Iran Seyyed Ebrahim Hosseini Zargaz ebrahimhosseini134zargaz@gmail.com 100319475328460011804 0009-0006-9048-3158 Yes Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran