en عمومى General پژوهشي Research <table align="left" cellpadding="0" cellspacing="0" hspace="0" vspace="0"> <tbody> <tr> <td align="left"> <p><strong>Introduction:</strong> The use of e-learning and computer-aided methods is rapidly on the rise in medical and nursing education. Therefore, given the conflicting findings and lack of systematic clinical trials on comparison of the effects of e-learning and traditional methods in nursing education, this study aimed to assess the effects of offline e-Learning on cognitive learning (levels of knowledge, comprehension, and application) in the Fluid and Electrolyte Imbalances course among nursing students.</p> <p><strong>Methods:</strong> This is a quasi-experimental study with a two-group, post-test-only design. A total of 52 third-semester nursing students were selected by convenience sampling method. Course contents were presented during 6 weeks by lecture and question and answer (Q & A) in the traditional learning group and by offline e-Learning in the second group. Afterwards, the students&rsquo; cognitive learning (knowledge, comprehension, and application) was assessed using a 23-item questionnaire on Fluid and Electrolyte Imbalances course. The obtained data were analyzed in SPSS (version 16) using Mann-Whitney, t-test, Chi-square, Fisher&#39;s Exact Test, and analysis of two-way variance. The significant level was considered as P < 0.05.</p> <p><strong>Results:</strong> The mean score of cognitive learning was significantly higher in the traditional learning group (14.1&plusmn;1.9) than in the e-learning group (12.4&plusmn;2.2) (P=0.006). The difference was also significant in the domain of knowledge (P<0.001), but insignificant in comprehension (P=0.097) and application (P=0.892) domains.</p> <p><strong>Conclusions:</strong> According to the results, the method of teaching e-learning, alongside traditional teaching method is recommended.</p> </td> </tr> </tbody> </table> <div style="clear:both;"></div> Cognitive learning, Nursing Students, e-Learning, Traditional learning 2 6 http://jsurgery.bums.ac.ir/browse.php?a_code=A-10-107-1&slc_lang=en&sid=1 Zahra Amouzeshi amoozeshiz9039@bums.ac.ir 10031947532846003152 10031947532846003152 No Faculty of Nursing and Midwifery, Surgery and Trauma Research Center, Birjand University of Medical Sciences,Birjand, Iran Narges Soltani soltani.n@bums.ac.ir 10031947532846003153 10031947532846003153 Yes Nursing and Midwifery Research Center, Birjand University of Medical Sciences, Birjand, Iran - Narjes Khatoon Taheri taherin@bums.ac.ir 10031947532846003154 10031947532846003154 No Department of Nursing, Gaen Faculty of Nursing and Midwifery, Birjand University of Medical Sciences, Birjand, Iran - Majid Zare Bidaki m.zare@bums.ac.ir 10031947532846003155 10031947532846003155 No Department of Microbiology, Birjand University of Medical Sciences, Birjand, Iran - Seyed Ali Reza Mousavi alireza.full72@gmail.com 10031947532846003156 10031947532846003156 No Graduate of Nursing, Birjand University of Medical Sciences, Birjand, Iran - Manizhe Nasirizade mnasirzadeh@bums.ac.ir 10031947532846003157 10031947532846003157 No Nursing and Midwifery Research Center, Birjand University of Medical Sciences, Birjand, Iran - Farzaneh Safajou 10031947532846003158 10031947532846003158 No Nursing and Midwifery Research Center, Birjand University of Medical Sciences, Birjand, Iran