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Hassan Mottaghi Moghaddam Shahri, Mohsen Yaghubi, Reza Ghasemi, Milad Chambari, Mahmood Hosseinzadeh Maleki,
Volume 10, Issue 2 (5-2022)

  • Introduction: Heart valve disease in pediatricsis an increasing global concern, especially in developing countries. This study aims to determine the clinical outcomes of pulmonary valve replacement (PVR) surgery in pediatrics.
  • Methods: The authors retrospectively identified all pediatrics undergoing PVR surgery at Imam Reza hospital (Mashhad, Iran) between 2000 and 2020. Their medical records were reviewed for demographic characteristics, clinical data (intra-operative and postoperative), and follow-up results. Echocardiography and electrocardiography were performedonall patients before the surgery and periodically after the surgery.
  • Results: Among 50 pediatrics undergoing surgical PVR, 38 (76%) were female and others were male (14%), with a mean age of 10.39±5.31 years. The leading cause of PVR was the Tetralogy of Fallot. There was a significant relationship between age at the time of surgery and the size of the pulmonary valve(P=0.02).There were also statistically significant differences between QTc intervals before and after surgery (P=0.001). Further more, there was a significant correlation between QTc intervals before and after surgery and the ageof pediatrics at the time of surgery (P=0.01, r=-0.6).There was also a statistically significant relationship between the ICU stay (P=0.01) and the weaning time of the mechanical ventilation (P=0.03).
  • Conclusion: It is recommended that this procedure ispostponed as much as possible to decrease postoperative life-threatening events in pediatrics.In addition, if this surgery is conducted with good surgical and nursing management, it can be safe with low complications among other cardiac valve procedures.

Feisal Rahimpour, Reza Ghasemi, Maryam Moradian, Mahmood Hosseinzadeh Maleki, Mohsen Yaghubi,
Volume 10, Issue 4 (12-2022)

  • The Tetralogy of Fallot is the most common cyanotic congenital heart disease that is often associated with chromosomal aberration had a high prevalence rate of all congenital heart diseases. The association of the Tetralogy of Fallot (ToF) with other congenital cardiac defects, especially with hypertrophic cardiomyopathy, is infrequent. While, unlike the tetralogy of Fallot, hypertrophic cardiomyopathy is accompanied by specific gene loci.
  • We report this scarce association in a 6-month male infant, cyanotic since birth and known with ToF, in her first hospital admission for treatment of recurring cyanotic crises. After the preliminary evaluations and the unsuccessful stenting of the patent ductus arteriousus (PDA) under an angiographic manner, he was prepared to undergo cardiac surgery to establish a modified Blalock-Taussig Shunt procedure. The patient was discharged in good condition and suggested that his parents follow up on his cardiac function after it. On follow-up at the age of three, the child had no cyanotic crises in this period.

Reza Ghasemi, Mahmood Hosseinzadeh Maleki, Saeideh Imani Moghaddam, Fatemeh Ramezani, Hamid Hoseinikhah, Mohsen Yaghubi,
Volume 10, Issue 4 (12-2022)

  • Introduction: Peripheral arterial disease in coronary artery disease (CAD) is associated with poor cardiovascular outcomes. This issue is more highlighted in patients undergoing coronary artery bypass graft surgery after catheterization procedures.
  • Methods: This study was observational on participants who recourse to the heart clinics and candidates for coronary angiography, based on inclusion and exclusion criteria. In the first, coronary angiography was performed, and so, if the patients had significant involvement of coronary arteries and had at least one inclusion criteria, for assessment of peripheral arterial disease (PAD), peripheral angiography through the femoral artery was performed. The statistical analysis was done by SPSS software (Version 16) and the data were analyzed using the descriptive statistics method, variance analysis, and Fisher's Exact Test. The level of significance was considered to be (0.05).
  • Results: Among all patients, there was no significant difference in the demographic variables such as gender (P= 0.497) and age (P= 0.069). The commonest peripheral artery involved in patients was the right femoral artery. A statistically significant relationship between gender and PAD was seen (P=0.001). There was no significant relationship between the type of involved coronary artery and gender (p=0.043; Fisher's Exact Test = 10.719).
  • Conclusion: More than one-third of participants with CAD had peripheral arterial involvement in iliofemoral arteries in this study. This situation increased the risk of complications in vascular blind catheterization. So, Improving PAD detection is crucial for more effective cardiovascular prevention and treatment.

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