Volume 13, Issue 2 (6-2025)                   J Surg Trauma 2025, 13(2): 80-83 | Back to browse issues page

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Soltani E, Majidi S, Hasanzadeh E, Jabbari Noghabi A. Scrotal Squamous Cell Carcinoma Secondary to Chronic Urinary Irritation: A Case Report with Inguinofemoral and Suprapubic Lymph Node Involvement. J Surg Trauma 2025; 13 (2) :80-83
URL: http://jsurgery.bums.ac.ir/article-1-466-en.html
Department of Surgery, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
Abstract:   (152 Views)
A 60-year-old man with a scrotal ulcer was referred to our Cancer Surgery Clinic. Biopsy was positive for squamous cell carcinoma (SCC), which should be considered even in clinically node-negative cases; therefore, the tumor was removed. In addition, adjuvant treatment was not performed. Three months later, the tumor recurred in the scrotum and inguinal regions. Surgical removal and bilateral lymphatic dissection were performed. Treatment was completed with radiotherapy. After one month, the tumor recurred in the suprapubic area, which was removed, and chemotherapy with “methotrexate” was started. After six months, there was no recurrence of the disease. According to other studies as well as our observations, in cases of SCC of the scrotum, sentinel lymph node biopsy should be used in cases with negative nodes, as well as full adjuvant treatments; local surgery is not sufficient.
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Type of Study: Case Report | Subject: Urology
Received: 2025/02/17 | Accepted: 2025/05/28 | ePublished ahead of print: 2025/06/10 | Published: 2025/06/17

References
1. Marietta M, Crane JS. Marjolin ulcer. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
2. Yao Zhu, Ding-Wei-Ye. Preneoplastic and primary scrotal cancer updates on pathogenesis and diagnostic evaluation. Urol Clin North Am. 2016; 43(4):523-30. [DOI:10.1016/j.ucl.2016.06.013]
3. Imrani K, Lahfidi A, Belkouchi L, Jerguigue H, Latib R, Omor Y. Scrotal verrucous carcinoma: An exceptional localization of a rare tumor. Case Rep Med. 2021; 2021:6651925. [DOI:10.1155/2021/6651925]
4. Debashis Sarkar. A systematic review of scrotal squamous cell carcinoma. EMJ Urol. 2019;7(1):68-74 [DOI:10.33590/emjurol/10314467]
5. Lam W, Alnajjar HM, La-Touche S, Perry M, Sharma D, Corbishley C, et al. Dynamic sentinel lymph node biopsy in patients with invasive squamous cell carcinoma of the penis: A prospective study of the long-term outcome of 500 inguinal basins assessed at a single institution. Eur Urol. 2013;63(4):657-63 [DOI:10.1016/j.eururo.2012.10.035]
6. Hogstedt C, Jansson C, Hugosson M, Tinnerberg H, Gustavsson P. Cancer incidence in a cohort of Swedish chimney sweeps, 1958-2006. Am J Public Health. 2013;103(9):1708-14. [DOI:10.2105/AJPH.2012.300860]
7. Wu C, Li Z, Guo S, Zhou F, Han H. Development and validation of a nomogram for the prediction of inguinal lymph node metastasis extranodal extension in penile cancer. Front Oncol. 2021; 11:675565. [DOI:10.3389/fonc.2021.675565]
8. Bazaliński D, Przybek-Mita J, Barańska B, Więch P. Marjolin's ulcer in chronic wounds - review of available literature. Contemp Oncol (Pozn). 2017;21(3):197-202. [DOI:10.5114/wo.2017.70109]
9. Essid MA, Bouzouita A, Saadi A, Blel A, Chaker K, Chakroun M, at al. A case report of scrotal squamous cell carcinoma secondary to chronic urinary irritation. Cureus. 2018;10(4):e2430. [DOI:10.7759/cureus.2430]
10. Žulpaitė G, Žulpaitė R, Vėželis A. Scrotal squamous cell carcinoma: a case report. J Surg Case Rep. 2023; 2023(3):rjad128. [DOI:10.1093/jscr/rjad128]
11. Junqueira AL, Wanat KA, Farah RS. Squamous neoplasms arising within tattoos: clinical presentation, histopathology and management. Clin Exp Dermatol. 2017; 42(6):601-6. [DOI:10.1111/ced.13183]

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