Volume 13, Issue 3 (9-2025)
J Surg Trauma 2025, 13(3): 103-110 |
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Mozafarmoghadam N, Zarban A, Saremi Z, Sharifzadeh G, Raeesi V. Serum Vitamin D Levels and Their Association with Osteoporosis in Kidney Transplant Recipients: A Cross-Sectional Study in Birjand, Iran, in 2022. J Surg Trauma 2025; 13 (3) :103-110
URL: http://jsurgery.bums.ac.ir/article-1-467-en.html
URL: http://jsurgery.bums.ac.ir/article-1-467-en.html
Negin Mozafarmoghadam 
, Asghar Zarban , Zeinab Saremi , Gholamreza Sharifzadeh , Vajehallah Raeesi *
, Asghar Zarban , Zeinab Saremi , Gholamreza Sharifzadeh , Vajehallah Raeesi *
Department of Internal Medicine, School of Medicine, Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
Abstract: (196 Views)
Introduction: Chronic Kidney Disease (CKD) is associated with mineral metabolism disorders, such as calcium, phosphorus, and calcium-regulating hormones. Moreover, the need to prescribe and use corticosteroid compounds increases the risk of osteoporosis in these patients. Therefore, this study aimed to investigate the serum level of Vitamin D and its relationship with osteoporosis in kidney transplant patients (KTPs) in Birjand, Iran.
Methods: This descriptive-analytical cross-sectional study included 50 KTPs in Birjand, Iran, who had passed at least one year after a kidney transplant. Vitamin D serum level and bone mineral density (BMD) were measured by the Dual-Energy X-Ray Absorptiometry method. Data analysis was done using SPSS software (version 19) and statistical tests, such as Fisher's exact test, chi-square, independent samples t-test, and Pearson correlation coefficient at α=0.05 level.
Results: Vitamin D level showed no significant relationship with BMD, T score, and Z score. The mean of Z SPINE, Z RAD, T SPINE, T HIP, and T RAD in women was significantly higher than that of men (P<0.05). Moreover, no statistically significant linear correlation of vitamin D levels was observed with T-score and Z-score indices according to age in the studied patients. Finally, the results showed no significant relationship of Vitamin D levels with BMD, T score, and Z score.
Conclusion: Considering that similar studies have been conducted at a limited level, it is suggested that more comprehensive studies be conducted to more accurately investigate and determine the relationship between Vitamin D and osteoporosis in KTPs.
Methods: This descriptive-analytical cross-sectional study included 50 KTPs in Birjand, Iran, who had passed at least one year after a kidney transplant. Vitamin D serum level and bone mineral density (BMD) were measured by the Dual-Energy X-Ray Absorptiometry method. Data analysis was done using SPSS software (version 19) and statistical tests, such as Fisher's exact test, chi-square, independent samples t-test, and Pearson correlation coefficient at α=0.05 level.
Results: Vitamin D level showed no significant relationship with BMD, T score, and Z score. The mean of Z SPINE, Z RAD, T SPINE, T HIP, and T RAD in women was significantly higher than that of men (P<0.05). Moreover, no statistically significant linear correlation of vitamin D levels was observed with T-score and Z-score indices according to age in the studied patients. Finally, the results showed no significant relationship of Vitamin D levels with BMD, T score, and Z score.
Conclusion: Considering that similar studies have been conducted at a limited level, it is suggested that more comprehensive studies be conducted to more accurately investigate and determine the relationship between Vitamin D and osteoporosis in KTPs.
Type of Study: Research |
Subject:
Urology
Received: 2025/02/18 | Accepted: 2025/08/16 | ePublished ahead of print: 2025/09/6 | Published: 2025/09/18
Received: 2025/02/18 | Accepted: 2025/08/16 | ePublished ahead of print: 2025/09/6 | Published: 2025/09/18
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