Ethics code: IR.BUMS.REC.1401.184
چکیده: (23 مشاهده)
Introduction: Chronic Kidney Disease (CKD) is associated with mineral metabolism disorders, such as calcium, phosphorus, and calcium-regulating hormones. Moreover, the need to prescribe and use corticosteroid compounds increases the risk of osteoporosis in these patients. Therefore, this study aimed to investigate the serum level of Vitamin D and its relationship with osteoporosis in kidney transplant patients (KTPs) in Birjand, Iran.
Methods: This descriptive-analytical cross-sectional study included 50 KTPs in Birjand, Iran, who had passed at least one year after a kidney transplant. Vitamin D serum level and bone mineral density (BMD) were measured by the Dual-Energy X-Ray Absorptiometry method. Data analysis was done using SPSS software (version 19) and statistical tests, such as Fisher's exact test, chi-square, independent samples t-test, and Pearson correlation coefficient at α=0.05 level.
Results: Vitamin D level showed no significant relationship with BMD, T score, and Z score. The mean of Z SPINE, Z RAD, T SPINE, T HIP, and T RAD in women was significantly higher than that of men (P<0.05). Moreover, no statistically significant linear correlation of vitamin D levels was observed with T-score and Z-score indices according to age in the studied patients. Finally, the results showed no significant relationship of Vitamin D levels with BMD, T score, and Z score.
Conclusion: Considering that similar studies have been conducted at a limited level, it is suggested that more comprehensive studies be conducted to more accurately investigate and determine the relationship between Vitamin D and osteoporosis in KTPs.
Methods: This descriptive-analytical cross-sectional study included 50 KTPs in Birjand, Iran, who had passed at least one year after a kidney transplant. Vitamin D serum level and bone mineral density (BMD) were measured by the Dual-Energy X-Ray Absorptiometry method. Data analysis was done using SPSS software (version 19) and statistical tests, such as Fisher's exact test, chi-square, independent samples t-test, and Pearson correlation coefficient at α=0.05 level.
Results: Vitamin D level showed no significant relationship with BMD, T score, and Z score. The mean of Z SPINE, Z RAD, T SPINE, T HIP, and T RAD in women was significantly higher than that of men (P<0.05). Moreover, no statistically significant linear correlation of vitamin D levels was observed with T-score and Z-score indices according to age in the studied patients. Finally, the results showed no significant relationship of Vitamin D levels with BMD, T score, and Z score.
Conclusion: Considering that similar studies have been conducted at a limited level, it is suggested that more comprehensive studies be conducted to more accurately investigate and determine the relationship between Vitamin D and osteoporosis in KTPs.
نوع مطالعه: پژوهشي |
موضوع مقاله:
ارولوژی
دریافت: 1403/11/30 | پذیرش: 1404/5/25 | انتشار الکترونیک پیش از انتشار نهایی: 1404/6/15
دریافت: 1403/11/30 | پذیرش: 1404/5/25 | انتشار الکترونیک پیش از انتشار نهایی: 1404/6/15
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