دوره 3، شماره 3 و 4 - ( 7-1394 )                   جلد 3 شماره 3 و 4 صفحات 59-57 | برگشت به فهرست نسخه ها

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Kayat R, Bijari E. Intestinal perforation in a patient with paroxysmal nocturnal hemoglobinuria. J Surg Trauma 2015; 3 (3 and 4) :57-59
URL: http://jsurgery.bums.ac.ir/article-1-72-fa.html
Intestinal perforation in a patient with paroxysmal nocturnal hemoglobinuria. نشریه جراحی و تروما 1394; 3 (3 و 4) :59-57

URL: http://jsurgery.bums.ac.ir/article-1-72-fa.html


چکیده:   (4208 مشاهده)

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias.Acute abdominal pain is one of the PNH clinical manifestations due to venous thrombosis of intra-abdominal sites including hepatic, portal, mesenteric, and splenic veins.Eculizumaband allogeneic bone marrow transplantation (BMT) arethe only widely effective therapies for these patients.

We report a case of PNH disorder which presented with abdominal pain and mild tenderness. Abdominal X ray and sonography revealed intra-peritonealfree fluid and air. At laparotomy, an ischemic segment of jejunum with stricture and perforationwith mesenteric venous thrombosis were found. The patient also had a history of hepatic vein thrombosis two years before.

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نوع مطالعه: گزارش مورد | موضوع مقاله: جراحی عمومی
دریافت: 1395/7/12 | پذیرش: 1395/9/6 | انتشار: 1395/10/5 | انتشار الکترونیک: 1395/10/5

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